Endoflip® system for Impedance Planimetry
EndoFLIP is a new imaging tool which employs a balloon catheter within which there is an array of electrodes, along with a balloon pressure sensor.
Using a technique known as impedance planimetry, the diameter at each electrode on the catheter can be estimated. When the balloon catheter is inserted into a hollow body an image, extending up to 80mm long, may be constructed in 5mm slices.
The EndoFLIP® (Endolumenal Functional Lumen Imaging Probe) Imaging System is a revolutionary new technology used to measure the dimensions and function of a variety of hollow organs and sphincteric regions throughout the gastrointestinal tract.
These measurements are useful for different types of patients such as:
- GORD patients
- Potential candidates for GORD surgery
- Bariatric surgery patients
By measuring pressure, "distensibility” can be calculated using the formula cross sectional area/balloon pressure. This indicates how much a stoma or sphincter stretches when challenged by the balloon when it is inflated to a given pressure.
This "compliance-like" figure differs from compliance, calculated as volume/pressure, which is more appropriate to a closed volume, such as a pouch for example. See below for example.
Impedance monitoring will have broad applications for gastroenterologists as well as those performing anti-reflux procedures. Impedance monitoring removes the need for assumptions by showing the actual bolus transit.
Seting Up EndoFLIP (part 1)
Seting Up EndoFLIP (part 2)
FLIP Analytics tool demonstration
|Title:||Esophagogastric Junction Distensibility After Fundoplication Assessed with a Novel Functional Luminal Imaging Probe|
|Author(s):||Monika A. Kwiatek, Peter J. Kahrilas, Nathaniel J. Soper, William J. Bulsiewicz, Barry P. McMahon, Hans Gregersen and John E. Pandolfino|
|Ref:||J Gastrointest Surg DOI 10.1007/s11605-009-1086-1|
|Title:||Do we really understand the role of the oesophagogastric junction in disease?|
|Author(s):||Barry P McMahon, Blair A Jobe, John E Pandolfino and Hans Gregersen|
|Ref:||World J Gastroenterol 2009 January 14; 15(2): 144-150|
|Title:||Esophagogastric junction distensibility: a factor contributing to sphincter incompetence|
|Author(s):||John E Pandalfino, Guoxiang Shi, Jennifer Curry, Raymond J Joehl, James G Brasseur and Peter J Kahrilas|
|Ref:||Am J Physiol Gastrointest Liver Physiol 282: G1052–G1058, 2002; 10.1152/ajpgi.00279.2001.|
|Title:||Esophagogastric junction opening during relaxation distinguishes nonhernia reflux patients, hernia patients and normal subjects|
|Author(s):||John E Pandalfino, Guoxiang Shi, Brian Trueworthy and Peter J Kahrilas|
|Title:||Functional oesophago-gastric junction imaging|
|Author(s):||Barry P McMahon, Asbjørn M Drewes and Hans Gregersen|
|Ref:||World J Gastroenterol 2006 May 14; 12(18): 2818-2824|
|Title:||Increased esophagogastric junction distensibility in GERD patients assessed with the endoscopically placed functional luminal imaging probe - abstract|
|Author(s):||Monika A Kwiatek, Ikuo Hirano, Peter J Kahrilas, Barry McMahon and John E Pandolfino|
|Title:||Restoration of normal distensive characteristics of the esophagogastric junction after fundoplication|
|Author(s):||John E Pandolfino, Jennifer Curry, Guoxiang Shi, Raymond J. Joehl, James G. Brasseur and Peter J. Kahrilas|
|Ref:||Ann Surg 2005;242: 43–48|
|Title:||The functional lumen imaging probe (FLIP) for evaluation of the esophagogastric junction|
|Author(s):||Barry P McMahon Jens B Frøkjær, Peter Kunwald, Donghua Liao, Peter Funch-Jensen, Asbjørn M. Drewes, and Hans Gregersen|
|Ref:||Am J Physiol Gastrointest Liver Physiol 292: G377–G384, 2007.|
|Title:||A new technique for evaluating sphincter function in visceral organs: application of the functional lumen imaging probe (FLIP) for the evaluation of the oesophago-gastric junction|
|Author(s):||Monika A. Kwiatek, Ikuo Hirano, Daniel Luger, Peter J., Kahrilas, Nirmala Gonsalves and John E. Pandolfino|
|Title:||The relationship between symptom response, esophageal eosinophilia and wall distensibility in eosinophilic esophagitis - A pilot study following proton pump inhibitor therapy|
|Author(s):||Monika A. Kwiatek, Ikuo Hirano, Daniel Luger, Peter J. Kahrilas, Nirmala Gonsalves and John E. Pandolfino|